Auranofin Inhibits the Enzyme Activity of Pasteurella multocida Toxin PMT in Human Cells and Protects Cells from Intoxication

by Stefan Carle, Thorsten Brink, Joachim H. C. Orth, Klaus Aktories, Holger Barth
Published 2017-01-01

Involvement of Osteocytes in the Action of Pasteurella multocida Toxin

by Hannah Heni, Julia K. Ebner, Gudula Schmidt, Klaus Aktories, Joachim H. C. Orth
Published 2018-08-01

Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis.

by Peter Siegert, Gudula Schmidt, Panagiotis Papatheodorou, Thomas Wieland, Klaus Aktories, Joachim H C Orth
Published 2013-01-01

Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins.

by Thorsten Brink, Veronika Leiss, Peter Siegert, Doris Jehle, Julia K Ebner, Carsten Schwan, Aliaksei Shymanets, Sebastian Wiese, Bernd Nürnberg, Michael Hensel, Klaus Aktories, Joachim H C Orth
Published 2018-08-01

Granzyme A Produces Bioactive IL-1β through a Nonapoptotic Inflammasome-Independent Pathway

by Dagmar Hildebrand, Konrad A. Bode, David Rieß, Daniela Cerny, Anna Waldhuber, Franziska Römmler, Julia Strack, Simone Korten, Joachim H.C. Orth, Thomas Miethke, Klaus Heeg, Katharina F. Kubatzky
Published 2014-11-01