A surprising new route to 4-nitro-3-phenylisoxazole

A one-pot synthesis of 4-nitro-3-phenylisoxazole has been carried out by treatment of cinnamyl alcohol dissolved in acetic acid with sodium nitrite; in addition, 4-phenyl-3-furoxanmethanol was obtained in 40% yield.

Bibliographic Details
Main Authors: Henning Hopf, Aboul-fetouh E. Mourad, Peter G. Jones
Format: Article
Language:English
Published: Beilstein-Institut 2010-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.6.68