CD47 regulates collagen I-induced cyclooxygenase-2 expression and intestinal epithelial cell migration.
Increased epithelial cell expression of the cyclooxygenase-2 (COX-2) enzyme is a characteristic event of both inflammatory bowel disease and colon cancer. We here report the novel findings that collagen I-induced de novo synthesis of COX-2 in intestinal epithelial cells is inhibited by pertussis tox...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-07-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2712095?pdf=render |