Inhibition of PERK pathway enhances sensitivity of human osteosarcoma HOS cells induced to pyropheophorbide-a methyl ester-mediated photodynamic therapy

Inhibition of PERK pathway enhances sensitivity of human osteosarcoma HOS cells induced to pyropheophorbide-a methyl ester-mediated photodynamic therapy

Objective To explore the role of RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) pathway in the crosstalk of apoptosis and autophagy in human osteosarcoma HOS cells induced by pyropheophorbide-a methyl ester-mediated photodynamic therapy (MPPa-PDT) and investigate the mechanism...

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Bibliographic Details
Main Authors: ZHONG Shenxi, OU Yunsheng, CHEN Yanyang, YU Haoyang, ZUO Qiang
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-01-01
Series:Di-san junyi daxue xuebao
Subjects:
rna-activated protein kinase-like endoplasmic reticulum kinase pathway
pyropheophorbide-a methyl ester
photodynamic therapy
human osteosarcoma hos cells
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201808197.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/201808197.htm

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