Afferent arteriole responsiveness to endothelin receptor activation: does sex matter?

Abstract Background The pathogenesis of hypertension is distinct between men and women. Endothelin-1 (ET-1) is a potential contributor to sex differences in the pathophysiology of hypertension. ET-1 participates in blood pressure regulation through activation of endothelin A (ETA) and endothelin B (...

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Bibliographic Details
Main Authors: Eman Y. Gohar, Anthony K. Cook, David M. Pollock, Edward W. Inscho
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Biology of Sex Differences
Subjects:
Sex
Online Access:http://link.springer.com/article/10.1186/s13293-018-0218-2