High-level integration of murine intestinal transcriptomics data highlights the importance of the complement system in mucosal homeostasis

High-level integration of murine intestinal transcriptomics data highlights the importance of the complement system in mucosal homeostasis

Abstract Background The mammalian intestine is a complex biological system that exhibits functional plasticity in its response to diverse stimuli to maintain homeostasis. To improve our understanding of this plasticity, we performed a high-level data integration of 14 whole-genome transcriptomics da...

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Bibliographic Details
Main Authors: Nirupama Benis, Jerry M. Wells, Mari A. Smits, Soumya Kanti Kar, Bart van der Hee, Vitor A. P. Martins dos Santos, Maria Suarez-Diez, Dirkjan Schokker
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Genomics
Subjects:
Pathway analysis
Transcriptomics
Data integration
Intestine
Complement pathway
Homeostasis
Online Access:https://doi.org/10.1186/s12864-019-6390-x

Internet

https://doi.org/10.1186/s12864-019-6390-x

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