Mitochondrial Carrier Homolog 2 Functionally Co-operates With BH3 Interacting-Domain Death Agonist in Promoting Ca2+-Induced Neuronal Injury

Mitochondrial Carrier Homolog 2 Functionally Co-operates With BH3 Interacting-Domain Death Agonist in Promoting Ca2+-Induced Neuronal Injury

The BH3 interacting-domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family. While proteolytic processing of BID links death receptor-induced apoptosis to the mitochondrial apoptosis pathway, we previously showed that full length BID also translocates to mitochondria during...

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Bibliographic Details
Main Authors: Beatrice D’Orsi, Natalia Niewidok, Heiko Düssmann, Jochen H. M. Prehn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
excitotoxicity
calcium
Bcl-2 family
cortical neurons
permeability transition pore (mPTP)
necrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.750100/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.750100/full

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