Rapid hepatic metabolism of 7-ketocholesterol in vivo: implications for dietary oxysterols

7-Ketocholesterol is a major dietary oxysterol and the predominant non-enzymically formed oxysterol in human atherosclerotic plaque. We tested the hypothesis that 7-ketocholesterol is preferentially retained by tissues relative to cholesterol in vivo. To ensure rapid tissue uptake, acetylated low de...

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Bibliographic Details
Main Authors: Malcolm A. Lyons, Samir Samman, Lissa Gatto, Andrew J. Brown
Format: Article
Language:English
Published: Elsevier 1999-10-01
Series:Journal of Lipid Research
Subjects:
rat
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349014