Molecular dynamics of retinoic acid-induced craniofacial malformations: implications for the origin of gnathostome jaws.

Molecular dynamics of retinoic acid-induced craniofacial malformations: implications for the origin of gnathostome jaws.

Intake of retinoic acid (RA) or of its precursor, vitamin A, during early pregnancy is associated with increased incidence of craniofacial lesions. The origin of these teratogenic effects remains enigmatic as in cranial neural crest cells (CNCCs), which largely contribute to craniofacial structures,...

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Main Authors: Maxence Vieux-Rochas, Laurent Coen, Takahiro Sato, Yukiko Kurihara, Yorick Gitton, Ottavia Barbieri, Karine Le Blay, Giorgio Merlo, Marc Ekker, Hiroki Kurihara, Philippe Janvier, Giovanni Levi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1876820?pdf=render

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http://europepmc.org/articles/PMC1876820?pdf=render

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