Ethnic related selection for an ADH Class I variant within East Asia.

The alcohol dehydrogenases (ADH) are widely studied enzymes and the evolution of the mammalian gene cluster encoding these enzymes is also well studied. Previous studies have shown that the ADH1B*47His allele at one of the seven genes in humans is associated with a decrease in the risk of alcoholism...

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Bibliographic Details
Main Authors: Hui Li, Sheng Gu, Xiaoyun Cai, William C Speed, Andrew J Pakstis, Efim I Golub, Judith R Kidd, Kenneth K Kidd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2268739?pdf=render