PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma

Abstract Altered energy metabolism of cancer cells shapes the immune cell response in the tumor microenvironment that facilitates tumor progression. Herein, we reported the novel of tumor cell-expressed Piwi Like RNA-Mediated Gene Silencing 1 (PIWIL1) in mediating the crosstalk of fatty acid metabol...

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Bibliographic Details
Main Authors: Ning Wang, Hor-Yue Tan, Yuanjun Lu, Yau-Tuen Chan, Di Wang, Wei Guo, Yu Xu, Cheng Zhang, Feiyu Chen, Guoyi Tang, Yibin Feng
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00485-8