MiR-361-3p inhibits β-amyloid accumulation and attenuates cognitive deficits through targeting BACE1 in Alzheimer's disease

The role of miR-361-3p in the pathology of Alzheimer’s disease is unknown. The target scan was used to screen potential target genes of miR-361-3p, and β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) was emphasized. Results from western blotting and reverse transcription-quantitativ...

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Bibliographic Details
Main Author: Yangfei Ji, Dan Wang, Boai Zhang, Hong Lu
Format: Article
Language:English
Published: IMR (Innovative Medical Research) Press Limited 2019-09-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1569287160791-1027641834.pdf