Genistein Inhibited Estradiol-Induced Vascular Endothelial Cell Injury by Downregulating the FAK/Focal Adhesion Pathway

Genistein Inhibited Estradiol-Induced Vascular Endothelial Cell Injury by Downregulating the FAK/Focal Adhesion Pathway

Background/Aims: In this study, we aimed to investigate the effects of genistein on the focal adhesion signaling pathway through its regulation of FAK. Genistein ultimately restored and alleviated estradiol-induced vascular endothelial injury. Methods: Microarray analysis was used to select differen...

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Bibliographic Details
Main Authors: Bing Liu, Lili Xu, Xinming Yu, Xuefei Jiao, Junwei Yan, Wei Li, Mingjin Guo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Estradiol
Vascular endothelial cells
Genistein
FAK
Online Access:https://www.karger.com/Article/FullText/493830

Internet

https://www.karger.com/Article/FullText/493830

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