Study on Co-Crystallization of LCZ696 Using In Situ ATR-FTIR and Imaging

In situ ATR-FTIR spectroscopy and imaging and image analysis were applied to the study of the multicomponent co-crystallization process involving <i>S</i>-valsartan and sacubitril in which LCZ696 crystals were formed. LCZ696 is a combination drug for use in heart failure that was approve...

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Bibliographic Details
Main Authors: Xiao Juan Liu, Yang Zhang, Xue Zhong Wang
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/10/10/922