The necessity of NEDD8/Rub1 for vitality and its association with mitochondria-derived oxidative stress

Access of molecular oxygen to the respiratory electron transport chain at the mitochondria costs in the generation of reactive oxygen-derived species (ROS). ROS induces progressive damage to macromolecules in all living cells, hence, rapid defense mechanisms to maintain cellular redox homeostasis ar...

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Bibliographic Details
Main Author: Elah Pick
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309708