The necessity of NEDD8/Rub1 for vitality and its association with mitochondria-derived oxidative stress
Access of molecular oxygen to the respiratory electron transport chain at the mitochondria costs in the generation of reactive oxygen-derived species (ROS). ROS induces progressive damage to macromolecules in all living cells, hence, rapid defense mechanisms to maintain cellular redox homeostasis ar...
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Format: | Article |
Language: | English |
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Elsevier
2020-10-01
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Series: | Redox Biology |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231720309708 |