The “Aging Factor” Eotaxin-1 (CCL11) Is Detectable in Transfusion Blood Products and Increases with the Donor’s Age

Background: High blood levels of the chemokine eotaxin-1 (CCL11) have recently been associated with aging and dementia, as well as impaired memory and learning in humans. Importantly, eotaxin-1 was shown to pass the blood-brain-barrier (BBB) and has been identified as crucial mediator of decreased n...

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Bibliographic Details
Main Authors: Julia Hoefer, Markus Luger, Christian Dal-Pont, Zoran Culig, Harald Schennach, Stefan Jochberger
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
age
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00402/full