Immune responses to HBsAg conjugated to protein D of non-typeable Haemophilus influenzae in mice.

BACKGROUND:Hepatitis B vaccine that contains an aluminum hydroxide adjuvant induces apoptotic death of Hepa 1-6 cells. Difficult-to-degrade chemical additives in vaccines effectively enhance vaccine immunogenicity, but also affect the host tissue. Identification of bio-molecules that are readily deg...

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Bibliographic Details
Main Authors: Qiudong Su, Yao Yi, Feng Qiu, Xuexin Lu, Junying Ding, Zhiyuan Jia, Ruiguang Tian, Yan Gao, Shengli Bi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4331537?pdf=render