The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes.

The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes.

<h4>Background</h4>After positive selection, the newly generated single positive (SP) thymocytes migrate to the thymic medulla, where they undergo negative selection to eliminate autoreactive T cells and functional maturation to acquire immune competence and egress capability.<h4>M...

Full description

Bibliographic Details
Main Authors: Fei Teng, Yubin Zhou, Rong Jin, Yu Chen, Xiaoyan Pei, Yuanfeng Liu, Jie Dong, Wei Wang, Xuewen Pang, Xiaoping Qian, Wei-Feng Chen, Yu Zhang, Qing Ge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22022412/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22022412/?tool=EBI

Similar Items