Effect of DHA and CoenzymeQ10 Against Aβ- and Zinc-Induced Mitochondrial Dysfunction in Human Neuronal Cells

Effect of DHA and CoenzymeQ10 Against Aβ- and Zinc-Induced Mitochondrial Dysfunction in Human Neuronal Cells

Background: Beta-amyloid (Aβ) protein is a key factor in the pathogenesis of Alzheimer's disease (AD) and it has been reported that mitochondria is involved in the biochemical pathway by which Aβ can lead to neuronal dysfunction. Coenzyme Q10 (CoQ10) is an essential cofactor involved in the mit...

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Bibliographic Details
Main Authors: Nadia Sadli, Colin J. Barrow, Sean McGee, Cenk Suphioglu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Zinc
Docosahexaenoic acid
CoenzymeQ10
Human neuronal cells
Neuroprotection
Mitochondrial function
Online Access:http://www.karger.com/Article/FullText/354433

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http://www.karger.com/Article/FullText/354433

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