A minimal model for structure, dynamics, and tension of monolayered cell colonies

Cells are in constant movement inside tissues, but often remain cohesive nevertheless, i.e., single cells do not escape from the colony edges. Using an active Brownian-particle model with attraction, in this paper the authors develop an interaction potential that reproduces experimental observations...

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Bibliographic Details
Main Authors: Debarati Sarkar, Gerhard Gompper, Jens Elgeti
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Physics
Online Access:https://doi.org/10.1038/s42005-020-00515-x