A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2

A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2

Summary: The influenza virus hemagglutinin (HA) and coronavirus spike (S) protein mediate virus entry. HA and S proteins are heavily glycosylated, making them potential targets for carbohydrate binding agents such as lectins. Here, we show that the lectin FRIL, isolated from hyacinth beans (Lablab p...

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Bibliographic Details
Main Authors: Yo-Min Liu, Md. Shahed-Al-Mahmud, Xiaorui Chen, Ting-Hua Chen, Kuo-Shiang Liao, Jennifer M. Lo, Yi-Min Wu, Meng-Chiao Ho, Chung-Yi Wu, Chi-Huey Wong, Jia-Tsrong Jan, Che Ma
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
lectin
influenza
coronavirus
SARS-CoV-2
antiviral
N-glycosylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720310019

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http://www.sciencedirect.com/science/article/pii/S2211124720310019

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