Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.

One of the two X chromosomes in female mammalian cells is subject to inactivation (XCI) initiated by the Xist gene. In this study, we examined in rodents (voles and rat) the conservation of the microsatellite region DXPas34, the Tsix gene (antisense counterpart of Xist), and enhancer Xite that have...

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Bibliographic Details
Main Authors: Alexander I Shevchenko, Anastasia A Malakhova, Eugeny A Elisaphenko, Nina A Mazurok, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3149622?pdf=render