Targeted Transcriptomics of Frog Virus 3 in Infected Frog Tissues Reveal Non-Coding Regulatory Elements and microRNAs in the Ranaviral Genome and Their Potential Interaction with Host Immune Response

Targeted Transcriptomics of Frog Virus 3 in Infected Frog Tissues Reveal Non-Coding Regulatory Elements and microRNAs in the Ranaviral Genome and Their Potential Interaction with Host Immune Response

BackgroundFrog Virus 3 (FV3) is a large dsDNA virus belonging to Ranaviruses of family Iridoviridae. Ranaviruses infect cold-blood vertebrates including amphibians, fish and reptiles, and contribute to catastrophic amphibian declines. FV3 has a genome at ~105 kb that contains nearly 100 coding genes...

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Bibliographic Details
Main Authors: Yun Tian, Collins N. Khwatenge, Jiuyi Li, Francisco De Jesus Andino, Jacques Robert, Yongming Sang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
frog virus 3
ranavirus
transcriptome
cis-regulatory elements
microRNA
interferon signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.705253/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.705253/full

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