Avian Influenza virus glycoproteins restrict virus replication and spread through human airway epithelium at temperatures of the proximal airways.

Avian Influenza virus glycoproteins restrict virus replication and spread through human airway epithelium at temperatures of the proximal airways.

Transmission of avian influenza viruses from bird to human is a rare event even though avian influenza viruses infect the ciliated epithelium of human airways in vitro and ex vivo. Using an in vitro model of human ciliated airway epithelium (HAE), we demonstrate that while human and avian influenza...

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Bibliographic Details
Main Authors: Margaret A Scull, Laura Gillim-Ross, Celia Santos, Kim L Roberts, Elena Bordonali, Kanta Subbarao, Wendy S Barclay, Raymond J Pickles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2673688?pdf=render

Internet

http://europepmc.org/articles/PMC2673688?pdf=render

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