Derivation and Validation of Age- and Body Mass Index-Adjusted Weight-Based Unfractionated Heparin Dosing

Derivation and Validation of Age- and Body Mass Index-Adjusted Weight-Based Unfractionated Heparin Dosing

Unfractionated heparin dosing is unpredictable and subject to numerous pharmacokinetic changes including distribution and metabolic changes associated with obesity and age. Weight-based dosing is commonly used to better predict the dose for a patient when targeting a therapeutic range. A dosing equa...

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Bibliographic Details
Main Authors: James W. Schurr PharmD, Anne-Marie Muske PharmD, Craig A. Stevens PharmD, Sarah E. Culbreth PharmD, Katelyn W. Sylvester PharmD, Jean M. Connors MD
Format: Article
Language:English
Published: SAGE Publishing 2019-03-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/1076029619833480

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https://doi.org/10.1177/1076029619833480

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