Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects.

Cardiovascular development is vital for embryonic survival and growth. Early gestation embryo loss or malformation has been linked to yolk sac vasculopathy and congenital heart defects (CHDs). However, the molecular pathways that underlie these structural defects in humans remain largely unknown hin...

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Bibliographic Details
Main Authors: Anjali K Nath, Michael Krauthammer, Puyao Li, Eugene Davidov, Lucas C Butler, Joshua Copel, Mikko Katajamaa, Matej Oresic, Irina Buhimschi, Catalin Buhimschi, Michael Snyder, Joseph A Madri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2626248?pdf=render