Congenic Strains Confirm the Pleiotropic Effect of Chromosome 4 QTL on Mouse Femoral Geometry and Biomechanical Performance.

Congenic Strains Confirm the Pleiotropic Effect of Chromosome 4 QTL on Mouse Femoral Geometry and Biomechanical Performance.

A pleiotropic quantitative trait locus (QTL) for bone geometry and mechanical performance in mice was mapped to distal chromosome 4 via an intercross of recombinant congenic mice HcB-8 and HcB-23. To study the QTL in isolation, we have generated C3H.B10-(rs6355453-rs13478087) (C.B.4.3) and C3H.B10-(...

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Bibliographic Details
Main Authors: Jasmin Kristianto, Suzanne J Litscher, Michael G Johnson, Forum Patel, Mital Patel, Jacqueline Fisher, Ryley K Zastrow, Abigail B Radcliff, Robert D Blank
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4743951?pdf=render

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http://europepmc.org/articles/PMC4743951?pdf=render

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