A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development.

The epithelial ureteric bud is critical for mammalian kidney development as it generates the ureter and the collecting duct system that induces nephrogenesis in dicrete locations in the kidney mesenchyme during its emergence. We show that a secreted Bmp antagonist Cerberus homologue (Cer1) fine tune...

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Bibliographic Details
Main Authors: Lijun Chi, Ulla Saarela, Antti Railo, Renata Prunskaite-Hyyryläinen, Ilya Skovorodkin, Shelagh Anthony, Kenjiro Katsu, Yu Liu, Jingdong Shan, Ana Marisa Salgueiro, José António Belo, Jamie Davies, Yuji Yokouchi, Seppo J Vainio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3219680?pdf=render