The Prohormone Proinsulin as a Neuroprotective Factor: Past History and Future Prospects

Proinsulin was first identified as the primary translation product of the insulin gene in Donald Steiner’s laboratory in 1967, and was the first prohormone to be isolated and sequenced. While its role as an insulin precursor has been extensively studied in the field of endocrinology, the bioactivity...

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Bibliographic Details
Main Authors: Flora de Pablo, Catalina Hernández-Sánchez, Enrique J. de la Rosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00426/full