Histone Modification of Embryonic Stem Cells Produced by Somatic Cell Nuclear Transfer and Fertilized Blastocysts

Histone Modification of Embryonic Stem Cells Produced by Somatic Cell Nuclear Transfer and Fertilized Blastocysts

Objective: Nuclear transfer-embryonic stem cells (NT-ESCs) are genetically identical to the donor’s cells; provide a renewable source of tissue for replacement, and therefore, decrease the risk of immune rejection. Trichostatin A (TSA) as a histone deacetylase inhibitor (HDACi) plays an important ro...

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Bibliographic Details
Main Authors: Fattaneh Farifteh, Mohammad Salehi, Mojgan Bandehpour, Nariman Mosaffa, Marefat Ghafari Novin, Taher Hosseini, Sedigheh Nematollahi, Mohsen Noroozian, Somayeh Keshavarzi, Ahmad Hosseini
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2013-01-01
Series:Cell Journal
Subjects:
Somatic Cell Nuclear Transfer
Trichostatin A
Epigenetics Modification
Online Access:http://celljournal.org/library/upload/article/af_82322236227653456223336424353357374233546-Farifteh-1.pdf

Internet

http://celljournal.org/library/upload/article/af_82322236227653456223336424353357374233546-Farifteh-1.pdf

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