Folate Functionalized PLGA Nanoparticles Loaded with Plasmid pVAX1-NH36: Mathematical Analysis of Release

Folate Functionalized PLGA Nanoparticles Loaded with Plasmid pVAX1-NH36: Mathematical Analysis of Release

Plasmid DNA (pVAX1-NH36) was encapsulated in nanoparticles of poly-dl-lactic-co-glycolic (PLGA) functionalized with polyethylene glycol (PEG) and folic acid (PLGA-PEG-FA) without losing integrity. PLGA-PEG-FA nanoparticles loaded with pVAX1-NH36 (pDNA-NPs) were prepared by using a double emulsificat...

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Bibliographic Details
Main Authors: Cindy Alejandra Gutiérrez-Valenzuela, Patricia Guerrero-Germán, Armando Tejeda-Mansir, Reynaldo Esquivel, Roberto Guzmán-Z, Armando Lucero-Acuña
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Applied Sciences
Subjects:
drug delivery
pVAX1-NH36
mathematical analysis
copolymer synthesis
leishmaniasis
folate nanoparticles
Online Access:http://www.mdpi.com/2076-3417/6/12/364

Internet

http://www.mdpi.com/2076-3417/6/12/364

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