Acipimox Administration With Exercise Induces a Co-feedback Action of the GH, PP, and PYY on Ghrelin Associated With a Reduction of Peripheral Lipolysis in Bulimic and Healthy-Weight Czech Women: A Randomized Study

Acipimox Administration With Exercise Induces a Co-feedback Action of the GH, PP, and PYY on Ghrelin Associated With a Reduction of Peripheral Lipolysis in Bulimic and Healthy-Weight Czech Women: A Randomized Study

Objective: Anti-lipolytic drugs and exercise are enhancers of growth hormone (GH) secretion. Decreased circulating free fatty acids (FFA) have been proposed to exert ghrelin-GH feedback loop after administration of an anti-lipolytic longer-acting analog of nicotinic acid, Acipimox (OLB, 5-Methylpyra...

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Bibliographic Details
Main Authors: Kvido Smitka, Jara Nedvidkova, Karel Vondra, Martin Hill, Hana Papezova, Vojtech Hainer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Endocrinology
Subjects:
eating disorders
exercise
growth hormone
ghrelin
microdialysis
olbetam
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00108/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00108/full

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