Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients

Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients

<p>Abstract</p> <p>Background</p> <p>Identification of predictive markers of response to treatment is a major objective in breast cancer. A major problem in clinical sampling is the variability of RNA templates, requiring accurate management of tumour material and subse...

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Bibliographic Details
Main Authors: Mathieu Marie-Christine, Sigal-Zafrani Brigitte, Vacher Sophie, Servant Nicolas, Barbaroux Catherine, Tran-Perennou Carine, Scott Véronique, Lehmann-Che Jacqueline, Gentien David, Valet Fabien, de Cremoux Patricia, Bertheau Philippe, Guinebretière Jean-Marc, Asselain Bernard, Marty Michel, Spyratos Frédérique
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Cancer
Subjects:
neoadjuvant setting
transcriptome
RT-qPCR
breast cancer
quality criteria
Online Access:http://www.biomedcentral.com/1471-2407/11/215

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http://www.biomedcentral.com/1471-2407/11/215

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