Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass
Abstract Background Succinic acid has great potential to be a new bio-based building block for deriving a number of value-added chemicals in industry. Bio-based succinic acid production from renewable biomass can provide a feasible approach to partially alleviate the dependence of global manufacturi...
Main Authors: | Lei Yang, Mikkel Møller Henriksen, Rasmus Syrach Hansen, Mette Lübeck, Jesper Vang, Julie Egelund Andersen, Signe Bille, Peter Stephensen Lübeck |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | Biotechnology for Biofuels |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13068-020-01850-5 |
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