Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass

Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass

Abstract Background Succinic acid has great potential to be a new bio-based building block for deriving a number of value-added chemicals in industry. Bio-based succinic acid production from renewable biomass can provide a feasible approach to partially alleviate the dependence of global manufacturi...

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Bibliographic Details
Main Authors: Lei Yang, Mikkel Møller Henriksen, Rasmus Syrach Hansen, Mette Lübeck, Jesper Vang, Julie Egelund Andersen, Signe Bille, Peter Stephensen Lübeck
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Biotechnology for Biofuels
Subjects:
Aspergillus niger
Metabolic engineering
Succinic acid production
CRISPR–Cas9 system
Online Access:https://doi.org/10.1186/s13068-020-01850-5

Internet

https://doi.org/10.1186/s13068-020-01850-5

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