A Component-Resolved Therapeutic Vaccine for Cockroach Allergy Made of Per a 9 and Transforming Growth Factor-β Homologue, an Immunosuppressive Protein of Brugia malayi

Allergen-specific-immunotherapy (ASIT) can cause long-term resolution of allergic diseases, reduces drug use and chances of new allergen sensitization. Nevertheless, therapeutic vaccine and data on ASIT efficacy for cockroach (CR) allergy are relatively scarce. In this study, efficacy and mechanism...

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Bibliographic Details
Main Authors: Pannathee Prangtaworn, Kodchakorn Mahasongkram, Atiporn Saeung, Urai Chaisri, Watee Seesuay, Onrapak Reamtong, Anchalee Tungtrongchitr, Wanpen Chaicumpa, Nitat Sookrung
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676558/full