The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes.

Myelin is essential for rapid saltatory conduction and is produced by Schwann cells in the peripheral nervous system and oligodendrocytes in the central nervous system. In both cell types the transcription factor Sox10 is an essential component of the myelin-specific regulatory network. Here we iden...

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Bibliographic Details
Main Authors: Julia Hornig, Franziska Fröb, Michael R Vogl, Irm Hermans-Borgmeyer, Ernst R Tamm, Michael Wegner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3814293?pdf=render