Hyperglycemia induces oxidative stress and impairs axonal transport rates in mice.

While hyperglycemia-induced oxidative stress damages peripheral neurons, technical limitations have, in part, prevented in vivo studies to determine the effect of hyperglycemia on the neurons in the central nervous system (CNS). While olfactory dysfunction is indicated in diabetes, the effect of hyp...

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Bibliographic Details
Main Authors: Ruchi Sharma, Eric Buras, Tomoya Terashima, Faridis Serrano, Cynthia A Massaad, Lingyun Hu, Brittany Bitner, Taeko Inoue, Lawrence Chan, Robia G Pautler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2956689?pdf=render