Flexibility of PCNA-protein interface accommodates differential binding partners.

The expanding roles of PCNA in functional assembly of DNA replication and repair complexes motivated investigation of the structural and dynamic properties guiding specificity of PCNA-protein interactions. A series of biochemical and computational analyses were combined to evaluate the PIP Box recog...

Full description

Bibliographic Details
Main Authors: Anthony M Pedley, Markus A Lill, V Jo Davisson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4103810?pdf=render