Genetic and environmental perturbations lead to regulatory decoherence

Correlation among traits is a fundamental feature of biological systems that remains difficult to study. To address this problem, we developed a flexible approach that allows us to identify factors associated with inter-individual variation in correlation. We use data from three human cohorts to stu...

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Bibliographic Details
Main Authors: Amanda Lea, Meena Subramaniam, Arthur Ko, Terho Lehtimäki, Emma Raitoharju, Mika Kähönen, Ilkka Seppälä, Nina Mononen, Olli T Raitakari, Mika Ala-Korpela, Päivi Pajukanta, Noah Zaitlen, Julien F Ayroles
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/40538