Wild type and mutant 2009 pandemic influenza A (H1N1) viruses cause more severe disease and higher mortality in pregnant BALB/c mice.

Wild type and mutant 2009 pandemic influenza A (H1N1) viruses cause more severe disease and higher mortality in pregnant BALB/c mice.

BACKGROUND: Pregnant women infected by the pandemic influenza A (H1N1) 2009 virus had more severe disease and higher mortality but its pathogenesis is still unclear. PRINCIPAL FINDINGS: We showed that higher mortality, more severe pneumonitis, higher pulmonary viral load, lower peripheral blood T ly...

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Bibliographic Details
Main Authors: Kwok-Hung Chan, Anna J X Zhang, Kelvin K W To, Chris C S Chan, Vincent K M Poon, Kunyuan Guo, Fai Ng, Qi-Wei Zhang, Virtual H C Leung, Annie N Y Cheung, Candy C Y Lau, Patrick C Y Woo, Herman Tse, Wailan Wu, Honglin Chen, Bo-Jian Zheng, Kwok-Yung Yuen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2966430?pdf=render

Internet

http://europepmc.org/articles/PMC2966430?pdf=render

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