Toward DNA-Based T-Cell Mediated Vaccines to Target HIV-1 and Hepatitis C Virus: Approaches to Elicit Localized Immunity for Protection

Toward DNA-Based T-Cell Mediated Vaccines to Target HIV-1 and Hepatitis C Virus: Approaches to Elicit Localized Immunity for Protection

Human immunodeficiency virus (HIV)-1 and hepatitis C virus (HCV) are major contributors to the global disease burden with many experts recognizing the requirement of an effective vaccine to bring a durable end to these viral epidemics. The most promising vaccine candidates that have advanced into pr...

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Bibliographic Details
Main Authors: Zelalem A. Mekonnen, Branka Grubor-Bauk, Makutiro G. Masavuli, Ashish C. Shrestha, Charani Ranasinghe, Rowena A. Bull, Andrew R. Lloyd, Eric J. Gowans, Danushka K. Wijesundara
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
DNA vaccine
hepatitis C
human immunodeficiency virus
HIV/AIDS
HCV
tissue-resident memory
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00091/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00091/full

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