Opposite estrogen effects of estrone and 2-hydroxyestrone on MCF-7 sensitivity to the cytotoxic action of cell growth, oxidative stress and inflammation activity

Opposite estrogen effects of estrone and 2-hydroxyestrone on MCF-7 sensitivity to the cytotoxic action of cell growth, oxidative stress and inflammation activity

There are many kinds of estrogens, and endogenous estrogens produce a variety of estrogen metabolites with similar structure but with different physiological effects after metabolism in vivo. Studies have shown that estrone (E1) widely occurs in the environment and animal-derived food. Because of it...

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Bibliographic Details
Main Authors: Shiying Xu, Jiadi Sun, Yinzhi Zhang, Jian Ji, Xiulan Sun
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Estrone
Estrogen metabolites
Estrogen effect
Metabolic site
Hydroxylation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651320315906

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http://www.sciencedirect.com/science/article/pii/S0147651320315906

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