Interactions between Retroviruses and the Host Cell Genome

Replication-defective retroviral vectors have been used for more than 25 years as a tool for efficient and stable insertion of therapeutic transgenes in human cells. Patients suffering from severe genetic diseases have been successfully treated by transplantation of autologous hematopoietic stem-pro...

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Bibliographic Details
Main Authors: Valentina Poletti, Fulvio Mavilio
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
HIV
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050117301080