Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer
<p>Abstract</p> <p>Background</p> <p>The cytochrome P450 (CYP) enzymes 2C19, 2D6, and 3A5 are responsible for converting the selective estrogen receptor modulator (SERM), tamoxifen to its active metabolites 4-hydroxy-tamoxifen (4OHtam) and 4-hydroxy-<it>N</it&g...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-06-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/10/313 |