Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer

<p>Abstract</p> <p>Background</p> <p>The cytochrome P450 (CYP) enzymes 2C19, 2D6, and 3A5 are responsible for converting the selective estrogen receptor modulator (SERM), tamoxifen to its active metabolites 4-hydroxy-tamoxifen (4OHtam) and 4-hydroxy-<it>N</it&g...

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Bibliographic Details
Main Authors: Lundgren Steinar, Geisler Jürgen, Gjerde Jennifer, Ekse Dagfinn, Varhaug Jan, Mellgren Gunnar, Steen Vidar M, Lien Ernst A
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/313