Genetic predisposition of donors affects the allograft outcome in kidney transplantation: Single-nucleotide polymorphism of aquaporin-11

Background: Aquaporin-11 (AQP11) is a novel member of the aquaporin family. Disruption of the murine Aqp11 gene causes severe proximal tubular injury and renal failure. The rs2276415 (G>A) single-nucleotide polymorphism in the human AQP11 gene results in glycine to serine substitution in a functi...

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Bibliographic Details
Main Authors: Ji In Park, Seung Hee Yang, Jung Pyo Lee, Seong Ho Yoo, Yon Su Kim
Format: Article
Language:English
Published: The Korean Society of Nephrology 2015-03-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211913215000030