Hydrogen Sulfide Ameliorates Lung Ischemia-Reperfusion Injury Through SIRT1 Signaling Pathway in Type 2 Diabetic Rats

Hydrogen Sulfide Ameliorates Lung Ischemia-Reperfusion Injury Through SIRT1 Signaling Pathway in Type 2 Diabetic Rats

Lung ischemia-reperfusion (IR) injury remains a significant factor for the early mortality of lung transplantations. Diabetes mellitus (DM) is an independent risk factor for 5-year mortality following lung transplantation. Our previous study showed that DM aggravated lung IR injury and that oxidativ...

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Bibliographic Details
Main Authors: Tao Jiang, Weiwei Yang, Hongli Zhang, Zhiqiang Song, Tianhua Liu, Xiangqi Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Physiology
Subjects:
hydrogen sulfide
SIRT1
lung ischemia-reperfusion injury
type 2 diabetes mellitus
Oxidative Stress
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00596/full

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https://www.frontiersin.org/article/10.3389/fphys.2020.00596/full

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