Development of Antibiotic Resistance during Simulated Treatment of Pseudomonas aeruginosa in Chemostats.

During treatment of infections with antibiotics in critically ill patients in the intensive care resistance often develops. This study aims to establish whether under those conditions this resistance can develop de novo or that genetic exchange between bacteria is by necessity involved. Chemostat cu...

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Bibliographic Details
Main Authors: Yanfang Feng, Caspar J Hodiamont, Reinier M van Hest, Stanley Brul, Constance Schultsz, Benno H Ter Kuile
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4752458?pdf=render