Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae
DDK, a conserved serine-threonine protein kinase composed of a regulatory subunit, Dbf4, and a catalytic subunit, Cdc7, is essential for DNA replication initiation during S phase of the cell cycle through MCM2-7 helicase phosphorylation. The biological significance of DDK is well characterized, but...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2017-11-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.117.300223 |