Characterization of Tumor Microenvironment in Lung Adenocarcinoma Identifies Immune Signatures to Predict Clinical Outcomes and Therapeutic Responses

Characterization of Tumor Microenvironment in Lung Adenocarcinoma Identifies Immune Signatures to Predict Clinical Outcomes and Therapeutic Responses

Background and ObjectiveIncreasing evidence has elucidated the clinicopathological significance of individual TME component in predicting outcomes and immunotherapeutic efficacy in lung adenocarcinoma (LUAD). Therefore, we aimed to investigate whether comprehensive TME-based signatures could predict...

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Bibliographic Details
Main Authors: Donglai Chen, Yifei Wang, Xi Zhang, Qifeng Ding, Xiaofan Wang, Yuhang Xue, Wei Wang, Yiming Mao, Chang Chen, Yongbing Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
lung adenocarcinoma
tumor microenvironment
signature
survival
therapeutic response
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.581030/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.581030/full

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